This document highlights the health impact of a variety of medical devices and health technologies that are in use around the world, such as SoloShot syringes, HEATmarker Vaccine Vial Monitors, Nifty Feeding Cups, Uniject injection systems, and safe water devices. Innovations that have been produced at a scale of million and billions of units as well as more recent product introductions addressing critical global health needs are featured.