Request for Application #2020-038: G6PD Mobile Results Interpretation App and Engine
Plasmodium (P.) vivax is the most common species of malaria in countries close to eliminating the disease. The two commercially available drugs that can cure P. vivax are contraindicated for individuals with low levels of an enzyme called glucose-6-phosphate dehydrogenase (G6PD). PATH and our partners have advanced a point-of-care diagnostic device to measure G6PD activity. This test device, known as the STANDARD™ G6PD Test, is manufactured by SD Biosensor (South Korea) and is now commercially available in several malaria-endemic countries. This product could be enhanced through digital connectivity to improve its use and workflow including patient data management, accurate results interpretation, quality control, and patient referral and monitoring.
The Diagnostics Program, in collaboration with Digital Square, seeks to develop a digital solution to successfully transfer and interpret data from the STANDARD G6PD Test device into a digital solution. Successful data transfer and interpretation is defined as user-friendly, accurate, and comprehensive. The digital solution would improve the test’s use and workflow and support clinical case management of malaria. PATH is requesting applications to partner with mobile health developers to develop, test, and implement solutions in a manner that will be interoperable with health systems in high-priority countries for malaria control and elimination.
RFP #2020-013 | Facility and Process Engineering Consultants
PATH is developing vaccines in various disease areas, including malaria, enteric diseases, and respiratory pathogens that could be bacterial, viral, or monoclonal antibodies. PATH is working with many partners in developing countries to support their facilities and quality systems to be compliant and efficient and increase global vaccine supply. To enable support of vaccine development and continued manufacturing of vaccines to meet global demand, PATH is seeking facility and process engineers. The purpose of this Request for Proposal is to have one or more broad Master Service Agreements in place through December 2023 to cover facility and process engineering needs for various PATH programs through individual work orders. Confirmation of interest is due by April 6, 2020 and proposals due by May 5, 2020.
Supplier Prequalification | 2020-2022
PATH is a global organization that works to accelerate health equity by bringing together public institutions, businesses, social enterprises, and investors to solve the world’s most pressing health challenges. With expertise in science, health, finance, technology, advocacy, and dozens of other specialties, PATH develops and scales innovative solutions—including vaccines, drugs, devices, diagnostics, and approaches to strengthening health systems worldwide. PATH in Kenya supports local governments, US government (USG) implementing partners, and local technical experts in the design and implementation of high quality, impactful programs.
PATH Kenya Country Program invites sealed applications from eligible candidates for purposes of prequalifying suppliers for goods and services, FY 2020-2022 under the following categories:
RFP #2020-014 | Master Service Agreement for Contract Research Organization of electronic Common Technical Document (eCTD)
US FDA mandated that all Investigational New Drug (IND) applicants and Master Files (MF) must be submitted using the eCTD format. PATH is looking for an organization who can serve as a partner in publishing electronic regulatory submissions. This partnership would be in the form of a Master Service Agreement and would apply to multiple projects for all types of electronic regulatory submissions. Confirmation of interest is due by March 27, 2020 and proposals are due by May 1, 2020.
MAPs for PrEP regulatory support organization | RFA #2020-010
PATH is seeking a regulatory support organization to lead preparation for and implementation of an initial pre-Investigational New Drug (IND) consultation with the United States Food and Drug Administration (FDA) in support of developing dissolving microarray patches for delivery of cabotegravir for HIV prevention. The regulatory services organization will work with PATH, Queen’s University Belfast, and a contract manufacturing organization to prepare a Chemistry, Manufacturing, and Controls data package, in addition to other materials needed for an initial pre-IND consultation with the FDA. Expression of interest and questions related to this RFA are due by March 2, 2020. Proposals are due by March 25, 2020.
MAPs for PrEP contract manufacturing organization | RFA #2020-006
With United States Agency for International Development funding, PATH is collaborating with Queen’s University Belfast and ViiV Healthcare to develop dissolving Microarray patches (MAPs also known as microneedle patches) for delivery of cabotegravir (CAB) for HIV prevention. MAPs are an easy-to-use, discreet delivery technology, which could improve adherence to HIV pre-exposure prophylaxis. PATH is seeking a contract manufacturing organization to establish a small-scale manufacturing process for CAB MAPs that could be used in the future to produce current Good Manufacturing Process CAB MAPs for a Phase 1 proof-of-concept clinical trial. Expression of interest, signed non-disclosure agreement, organization description, and fact finding questions are due by March 10, 2020. Proposals are due by April 9, 2020.
Toxicology of PATH Vaccine Candidate | RFP #2020-003
PATH is developing vaccines in different disease areas which include malaria, enteric diseases, and respiratory pathogens. Prior to entering clinical trials PATH is planning on initiating multiple Toxicology studies which may include (a) repeat-dose toxicity and/or (b) reproductive toxicology studies, depending on the specific vaccine product, within the next two years. To enable support of vaccine development, PATH is seeking a contract research organization (CRO) to conduct toxicology studies in appropriate animal species based on the project according to Good Laboratory Practice (GLP). These may include acute toxicity studies that are IND enabling or reproductive toxicology as needed for specific programs. The intention is to first put a broad MSA in place with the CRO, and then subsequently develop Work Orders for specific scopes of work that would be attached to the MSA as per the needs of vaccine development program. Confirmation is due by February 11, 2020 with proposals due by March 5, 2020.
A Mixed Method Study to Improve the Outcome of Mass Drug Administration in Two Districts of Uttar Pradesh That Failed the Transmission Assessment Survey | RFP #2020-001
Lymphatic filariasis (LF) is a serious public health problem in India and it contributes to 40% of the global burden of Lymphatic Filariasis. Mass drug administration (MDA) is the recommended strategy by World Health Organization to achieve the goal of elimination of LF and is a feasible and cost-effective approach to put an end to one of the world’s leading causes of avoidable disability. Uttar Pradesh is one of the high priority states that accounts for one-third of total districts (157) with persistent transmission of filariasis. PATH India country office is supporting the Government of India and Government of Uttar Pradesh for implementation of program for elimination of Lymphatic Filariasis.
The research study intends to identify the reasons for poor compliance of community members for drugs distributed during MDA campaigns and failure of districts during Transmission Assessment Surveys in Uttar Pradesh. PATH would like to hire a survey agency for the data collection process, which include data collection, cleaning, collation, data analysis, and submission to PATH India in two phases through March 2020 – January 2021. The various forms of data collection will be household surveys, drug administrator surveys, focus group discussions, in-depth interviews, and ethnography surveys. Confirmation of interest is due by January 7, 2020 and proposals due January 15, 2020.
Request for proposals for app development | RFP # 2018-018
PATH is seeking a software development vendor to develop a mobile application (app) for use in South Africa. The purpose of this app is to provide a more available version of the United States President’s Emergency Plan for AIDS Relief’s (PEPFAR’s) monitoring, evaluation, and reporting (MER) reference guide to its implementing partners, which are required to report on PEPFAR indicators in South Africa.
This application will serve as a reference app to help standardize and improve the monitoring, reporting, and usage of MER indicators in South Africa. The app will equip PEPFAR partners with a reference app that guides them through the indicator reporting requirements and how they link to the South African context (e.g., national guidelines, national protocols, and data sources for South Africa). A mobile app will allow users to access content when they are offline. Ultimately, the goal is that this reference will help partners more effectively report on improvements in HIV/AIDS service delivery.
Additional details and requirements are identified in the RFP and in a separate requirements document. Interested eligible organizations are invited to review the RFP below and confirm interest of participating in the bidding process no later than June 11, 2018. Proposals are due by June 26, 2018.
All of our requests for proposals adhere to our principles for procurement operations.
Digital Health Data Use Partnership – Development of Administrative Area Registry System (AReS) for Government of Tanzania
The Government of Tanzania’s Data Use Partnership (DUP), a Tanzania Government-led initiative that is improving the national health care system through better use of health information, is looking to engage an organization or consortium of organizations with relevant software development and Geographic Information Systems (GIS) expertise to implement an administrative area registry system (AReS) software with the purpose of facilitating the continual update and accessibility of administrative area list and boundaries (e.g. villages, wards, and districts) for the Government of Tanzania. This effort is expected to benefit both the health sector and other sectors by ensuring consistency of administrative area data, thereby enabling better data comparability and exchange. This project will involve reviewing business processes, requirements, and user scenarios defined by the Government of Tanzania for AReS and working closely with the President's Office, Regional Administration, and Local Government (PORALG), other Government institutions, the DUP team, and PATH throughout the assignment. In addition to developing the AReS software, detailed business requirements, software development plans, refined requirements and technical specifications, process mapping, and training materials will be required.
Additional details and requirements are identified in the RFP. Interested eligible parties are invited to review the RFP below and send fact-finding questions by June 1, 2018. Proposals are due by June 15, 2018.
All of our requests for proposals adhere to our principles for procurement operations.
All requests for proposals adhere to our principles for procurement operations:
PATH subscribes to principles of simplicity and economy in procurement operations. We strive to obtain goods and services of the requisite type and quality within the time prescribed and at the lowest practical cost. We conduct purchasing activities in a manner that provides open and free competition to the maximum extent practical. We provide equal opportunity to participate to small and disadvantaged businesses, minority-owned firms, and women’s business enterprises. For information on registering as a small business, please see the US Small Business Administration’s contracting guide.
We endeavor to perform all procurement activities in a manner that will build or maintain good donor and business relations while furthering the mission of our organization. We maintain a standard of conduct that complies with US government procurement integrity regulations, anti-terrorism regulations, and Equal Employment Opportunity legislation.