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  1. Human papillomavirus (HPV) vaccine is intended to prevent cervical cancer. As part of project Optimize, a two-year HPV vaccine demonstration project is being conducted to demonstrate how existing delivery systems can be adapted to successfully provide HPV vaccine to young adolescent girls. HPV vaccine is a strong candidate for out-of-the-cold-chain use given its characteristics of high heat stability and freeze sensitivity.
    Published: July 2010
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  2. PATH conducted a market study in 2008 to identify neonatal resuscitators available in the Southern African Development Community region. These resuscitators are included in this region-specific version of Practical Selection of Neonatal Resuscitators. All resuscitators identified were bag-and-mask designs. Also included are two devices that offer a tube-and-mask design. This guide presents the criteria used during the device evaluation, evaluation results for each device, and suggestions for choosing a resuscitator. The guide is available in two formats: one for booklet-style printing and one for onscreen viewing.
    Published: June 2010
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    Part of a Series
  3. This handbook is a practical guide developed for site-level microbicide researchers, communicators, advocates, and others working on HIV prevention trials in developing countries. It includes context-specific case studies and practical insights from actual clinical trial communications initiatives. It is being updated to include work sheets and slide sets. To apply for a complimentary copy, please email Jacqueline Borodan at jacqueline@avac.org for detailed instructions.
    Published: May 2010
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  4. This report covers a 2009 consultation in Kampala, Uganda, that was convened by the Global Campaign for Microbicides, the Joint UN Programme on HIV/AIDS, and the US Centers for Disease Control and Prevention. It includes recommendations related to key ethical and practical questions on the design and implementation of clinical trials.
    Published: May 2010
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  5. Both Iran and Sudan utilize an alarm-based temperature recording system to monitor the performance of their national immunization cold stores. To better the utility and application of such systems in other countries, this project Optimize report documents the benefits, challenges, and advantages of both Iran’s and Sudan’s systems.
    Published: May 2010
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