Resources

While two malaria vaccines are now recommended by the World Health Organization for use in African children, there remains a need for next-generation vaccines that are more efficacious, durable, and cost-effective, and that require fewer doses.One promising approach is the development of multistage vaccines targeting both the pre-erythrocytic and asexual blood stages of the malaria parasite’s lifecycle. In May 2023, under the Innovations in Malaria Vaccine Development contract, the US Agency for International Development’s Malaria Vaccine Development Program and PATH convened a panel of experts in malaria, vaccine development, regulatory affairs, and the conduct of clinical trials in Africa, Europe, and the United States to consider and inform the development of a comprehensive clinical development plan for a multistage malaria vaccine.This report summarizes the discussions held during the consultation and outlines the experts' key recommendations to inform a clinical development plan.

Advocacy is a powerful tool for advancing health conversations to policy action and budget allocations. Since 2002, PATH has partnered with the Government of Uganda to implement impactful projects and programs that promote health equity. Our policy advocacy agenda in Uganda has been critical in supporting the adoption, implementation and financing of smart policies that advance the realization of universal health coverage in Uganda. In the second half of 2023, PATH’s advocacy and policy team in Uganda undertook an effort to comprehensively document its tremendous impact on policies for women and children over the past five years. Most of the policy advocacy achievements documented were a result of strong collaboration and partnerships with key decision-makers in government, including both elected and appointed leaders (political and technical), the media, the private sector, and the civil society organizations that continue to passionately advance the advocacy agenda with a strong focus on universal health coverage (UHC). The resources and videos below are the result of this process and were shared with PATH’s key stakeholders at a high-level national learning event.

PATH Kenya, through the U.S. President's Emergency Plan for AIDS Relief/U.S. Agency for International Development (USAID)-funded Nuru Ya Mtoto project, has been advancing a comprehensive suite of health, education, economic empowerment, and social services for orphans and vulnerable children (OVC) and their caretakers. The aim is to reduce vulnerability to HIV and contribute to their overall well-being.This brief provides an overview of the process USAID Nuru Ya Mtoto undertook, in collaboration with national and county government stakeholders, local implementing partners, and community health workers, to optimize and advance a whole-of-system suite of interventions to improve service coverage among OVC households and enhance household resiliency, by facilitating graduation from USAID Nuru Ya Mtoto's OVC program.

PATH helps policymakers and advocates make evidence-based policy and funding decisions to advance health equity. Leveraging PATH’s nearly 50 years of experience developing and delivering health innovations and services for women and children, PATH advocates collect, analyze, package, and use data to inform policies, mobilize resources, engage citizens, and hold decision-makers accountable to help women and children around the world survive and thrive.

Poor water, sanitation, and hygiene practices contribute to the spread of infections and negative health outcomes in communities and health care settings. Globally, roughly 3.85 billion people use health facilitates that lack basic hand hygiene services, while 1.7 billion people access health facilities that lack basic water services. Achieving the United Nations Sustainable Development Goal 6 (SDG 6)—ensuring access to water and sanitation for all—demands innovative and strategic solutions.One such solution is the Aqua Research STREAM™ Disinfectant Generator (STREAM). The STREAM is an onsite chlorine generator that uses common salt and water to generate liquid chlorine that meets global standards for intermediate–level disinfection of surfaces in health care settings and can be used for treating drinking water.With funding from the Conrad N. Hilton Foundation and in collaboration with ministries of health, this learning brief series provides real–world examples and lessons learned from implementing the STREAM in three countries: Ghana, Uganda, and Ethiopia.It describes how PATH, in collaboration with ministries of health, is using the SDG 6 Global Accelerator Framework to introduce and scale up the STREAM on a national level.