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Malawi

  1. The trial aimed to determine how well a new, injectable, non-replicating rotavirus vaccine candidate works compared to a licensed oral rotavirus vaccine in preventing infant diarrhea.
    Published: August 2022
    Type: Announcement
  2. In places with limited testing capacity, environmental surveillance of sewage and surface water may offer early warnings of outbreaks.
    Published: August 2022
    Type: Article
  3. In many low- and middle-income countries, hundreds of thousands of people—including many newborns, children, and pregnant women—die needlessly each year from hypoxemia, or a low concentration of oxygen in the blood. Hypoxemia can be caused by a range of illnesses and complications, including pneumonia, neonatal infections, premature birth, obstetric emergencies, and respiratory infections like COVID-19.The COVID-19 pandemic has pointedly highlighted the lack of access to oxygen in lower-resource settings. The biggest barriers to oxygen therapy access include inadequate supply and human resource capacity, funding constraints, and the inability to deploy resources in countries rapidly in a way that ensures maximum impact while not overwhelming existing health care systems. The oxygen landscape is at a pivotal point where short-term pandemic-response efforts require continued support while transitioning to long-term, sustained strategies for ensuring access.This fact sheet offers an overview of the SOURCE project to support countries to equitably improve access to high-quality oxygen services at all levels of the health care system in order to reduce maternal, child, and overall mortality from hypoxemia-related causes. To do so, PATH will incorporate near-term pandemic-response work into a robust set of implementation, advocacy, and research activities that will ensure long-term access to medical oxygen and resilient systems for future pandemic-response efforts.
    Published: July 2022
    Type: Resource Page
  4. Current live, oral rotavirus vaccines (LORVs) are reducing severe diarrhea in all settings, but they are not as effective in places with the highest burden. Alternative approaches in advanced clinical development include injectable next-generation rotavirus vaccines (iNGRVs), which have the potential to better protect children against disease, be combined with existing routine immunizations, and be even more affordable than the current LORVs. PATH conducted a series of studies to understand the real public health value of iNGRVs to help inform decisions by international agencies, funders, vaccine manufacturers, and countries. This included a feasibility and acceptability study with national stakeholders and healthcare providers in Ghana, Kenya, Malawi, Peru, Senegal, and Sri Lanka to assess their preferences for different hypothetical rotavirus vaccine options. These briefs provide an overview of the results in each of the study countries.
    Published: June 2022
    Type: Resource Page
  5. Current live, oral rotavirus vaccines (LORVs) are reducing severe diarrhea in all settings, but they are not as effective in places with the highest burden. Alternative approaches in advanced clinical development include injectable next-generation rotavirus vaccines (iNGRVs), which have the potential to better protect children against disease, be combined with existing routine immunizations, and be even more affordable than the current LORVs. PATH conducted a series of studies to understand the real public health value of iNGRVs to help inform decisions by international agencies, funders, vaccine manufacturers, and countries. This included: targeted analyses on the ideal age group for iNGRVs and potential future combination vaccine options, impact and cost effectiveness analyses, a feasibility and acceptability study with national stakeholders and healthcare providers in six countries, and a demand forecast. This brief provides a comprehensive summary of the results.
    Published: June 2022
    Type: Resource Page
  6. PATH is working with partners in Ghana, Kenya, Malawi, and Uganda to increase vaccine uptake and save lives.
    Published: April 2022
    Type: Article
  7. These case studies are designed to share country journeys to establish inpatient newborn care services and to provide practical guidance in low- and middle-income settings around the world. This series is comprised of four case studies conducted in Ethiopia, India, Malawi, and Rwanda, as well as a global overview document.
    Published: February 2022
    Type: Resource Page
  8. These case studies are designed to share country journeys to establish inpatient newborn care services and to provide practical guidance in low- and middle-income settings around the world. This series is comprised of four case studies conducted in Ethiopia, India, Malawi, and Rwanda, as well as a global overview document.
    Published: February 2022
    Type: Resource Page
  9. PATH and partners are helping countries make better investments in digital health by learning from those leading the way.
    Published: November 2021
    Type: Article
  10. Countries have to determine how to make the best use of limited resources. PATH uses health economics to inform countries' decisions about vaccines.
    Published: November 2021
    Type: Article
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