Pharmacokinetics and Tolerability of iOWH032, an Inhibitor of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channel, in Normal Volunteers and Cholera Patients

This poster presentation from Digestive Disease Week 2014 summarizes the results of a study comparing the pharmacokinetic profiles of a single dose of 300 mg iOWH032 in healthy American volunteers, healthy Bangladeshi volunteers, and Bangladeshi cholera patients with severe diarrhea. In addition, the safety of iOWH032 was assessed in these different populations.

Publication date: April 2014

Pharmacokinetics and Tolerability of iOWH032, an Inhibitor of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channel, in Normal Volunteers and Cholera Patients

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