The Data Use Partnership (DUP) is a Tanzanian Government–led initiative that is improving the national health care system through better digital health systems and the use of health information. DUP aims to strengthen digital health and build local capacity so that everyone—from government officials to health workers to patients—can take more informed action to improve health, leading to a healthier Tanzania. This brief summarizes how the Government of Tanzania, through the DUP initiative, is working to digitalize primary health care so that health workers can identify, track, and support patients across the continuum of care, whether a mother is visiting the clinic for her first antenatal care visit or taking her child for a lifesaving vaccine. Applying digital health solutions to primary health care can enhance health service delivery; enable evidence-based actions based on high-quality, real-time data; and improve patient care.