Malaria progress off track

According to the 2025 World Malaria Report, global progress in reducing malaria deaths is falling far short. In 2024, there were 610,000 deaths—more than 3 times the global target—and an estimated 282 million cases. The report highlights intensifying risks to malaria control, including antimalarial drug resistance, parasite gene deletions that undermine diagnostic tests, insecticide resistance that reduces the effectiveness of bed nets, and the invasive mosquito Anopheles stephensi, which poses a serious challenge to urban malaria control. Extreme weather events, shifting temperatures and rainfall, and conflict and instability are also driving outbreaks and disruptions to health services. Meanwhile, global funding for malaria has plateaued at less than half the target set by the Global Technical Strategy, with recent reductions in development assistance severely impacting interventions.

PATH’s commitment

PATH is dedicated to reversing stalled progress and addressing these growing threats. Our 2026-2030 strategy prioritizes strong alignment and coordination within the global malaria ecosystem. Central to this strategy are seven core pillars, recognized globally as essential to driving transmission down to zero. These pillars align with the RBM Partnership Big Push Framework, the WHO Global Technical Strategy, and the 2024 Yaoundé Declaration for a Big Push against malaria endorsed by African Ministers of Health.

Through coordinated action and strategic alignment, PATH aims to maximize resources and achieve the greatest impact in the fight against malaria.