
Despite significant progress over the last few decades, maternal and newborn deaths remain unacceptably high, with sub-Saharan Africa bearing the greatest burden. Most of these deaths are preventable. With collective action, political will, and high-quality care, we can rewrite the ending for millions of women and children.

Typhoid causes more than 93,000 deaths worldwide each year. In typhoid-endemic countries, the World Health Organization recommends typhoid conjugate vaccines (TCVs) for long-lasting protection. In Kenya, PATH is helping reach more than 21 million children with TCVs during the ongoing campaign. And in Burkina Faso, we supported a TCV campaign that reached 10 million children.

Scientists know the next pandemic is not a case of if but when. This is the driving force behind the 100 Days Mission—a plan for developing a new vaccine against a novel threat in just three months. The effort is spearheaded by the Coalition for Epidemic Preparedness Innovations (CEPI) and has been embraced by the global health community. As part of the mission, CEPI is teaming up with PATH to tackle a high-stakes challenge: reducing the time it takes to collect biological samples from survivors.

Maternal, newborn, and child health services are one of global health’s best investments. Since 2000, highly effective, low-cost solutions have helped reduce preventable maternal deaths by nearly 40 percent and child deaths by more than half. Today, as many donor countries scale back global health budgets, governments and donors are navigating tough choices. In a new series, we break down what the shifting financial landscape could mean for mothers and children.

Can artificial intelligence help health workers deliver better care? This month, PATH and partners launched a groundbreaking clinical trial in Nairobi, Kenya, to evaluate whether AI can improve patient outcomes, reduce misdiagnoses, and enhance clinician workflows in real-world health care settings.

At PATH, we help people access the products and services that make healthy lives possible. This includes vaccinating millions of children, providing essential treatment for people living with HIV, improving malaria treatment and prevention, and developing innovative solutions to save mothers’ lives. Right now, because of the US pause on foreign assistance, this work is at risk.

From advancing disease surveillance systems to equipping frontline health workers with AI tools, 2024 was a year of impact and innovation at PATH. In this month’s newsletter, we reflect on these and other highlights from 2024. We also celebrate Kent Campbell’s legacy and explore how data engineering is driving public health progress.

In this month’s newsletter, we’re sharing a roundup of PATH’s progress toward UHC2030—the global movement to build stronger health systems for UHC—by spotlighting integration of HIV into health systems to enable UHC. We also highlight our recent webinar exploring sustainable HIV financing.

In this edition of PATH Insights, we look at how stronger local manufacturing capabilities and digital health systems can improve prevention and response to infectious disease outbreaks like mpox. We also explore how AI can improve health care delivery in Africa, and the economics behind vaccines.

Mpox has affected the Democratic Republic of the Congo (DRC) for decades, but the current outbreak is the most urgent yet, threatening communities across Africa and beyond. Our latest article explains how PATH is supporting the DRC’s mpox response. This month, we also examine the worsening crisis of antimicrobial resistance and share a new set of tools decision-makers can use to assess vaccine costs.

PATH delegates travel to New York for the 79th United Nations General Assembly, joining global leaders and partners to discuss the most pressing issues in global health—from women’s health and climate change to artificial intelligence and antimicrobial resistance. This month, we also share news about PATH’s inaugural Chief AI Officer, a Q&A on the future of women’s health, and a story from PATH’s renowned workshop.

This month we’re highlighting a new vaccine that could end meningitis outbreaks in Africa and how PATH’s approach to policy advocacy helps address barriers in health.

In this month's Insights, we're celebrating Pride Month and exploring the gender health gap. Laurie Werner, Director, Center of Digital and Data Excellence (CoDE) also shares her four takeaways from WHA77 and its surrounding events—the World Summit on the Information Society and Geneva Digital Health Day.

This month, we’re sharing a photo essay from our entomological team’s 24-hour mosquito-collecting mission in Zambia, and new pieces on lifesaving malaria services and gender equity in health care.

Immunization systems are the backbone of primary health care. Investing in immunization requires investing in health care workers, supply chains, and a platform that can deliver other necessary health services. With World Immunization Week and World Malaria Day this month, we’re highlighting key milestones in our collaborative efforts to develop and introduce lifesaving vaccines.