Efforts to reduce transmission and eliminate malaria require an understanding of biology and transmission. A model to induce gametocytes to understand their dynamics and evaluate transmission-blocking interventions is currently unavailable. Here, we explore the use of the Controlled Human Malaria Infection model to induce gametocyte carriage with antimalarial drug regimens.
Author(s): Reuling I, van de Schans L, Coffeng L, Lanke K, Graumans W, van Gemert G, Teelen K, Siebelink-Stoter R, van de Vegte-Bolmer M, de Mast Q, van der Ven A, Ivinson K, Hermsen C, de Vlas S, Bradley J, Collins K, Ockenhouse C, McCarthy J, Bousema T,. Sauerwein
Corporate author(s): PATH, Radboud University Medical Center, University Medical Center Rotterdam, London School of Hygiene and Tropical Medicine, QIMR Berghofer
Publication date: November 2017
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This publication is part of the series ASTMH posters
Related regions: Global
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