Development of a Diagnostic Assay Based on the Binding of High-Risk HPV-E6 Oncoproteins to PDZ

A prototype of a novel diagnostic assay for cervical pre-cancer and cancer has been developed in both a sandwich ELISA-based and a lateral flow–based format (“strip test”). The test specifically detects presence of high-risk HPV-E6 and therefore promises to be of higher predictive value for cervical pre-cancer and cancer than other assays detecting merely presence of HPV. Presented at: 22rd International Papillomavirus Conference and Clinical Workshop, September 1, 2006; Vancouver, Canada.

Author(s): Schweizer J, Somoza C, Peck R, et al

Corporate author(s): PATH, Arbor Vita Corporation

Publication date: September 2006

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English

Development of a Diagnostic Assay Based on the Binding of High-Risk HPV-E6 Oncoproteins to PDZ (poster)

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Region: Global

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