Affordable, accessible, lifesaving drugs
Every day in the developing world, people’s lives are cut short or severely compromised because they don’t have access to safe and effective medicines. The right drugs may be too costly, or they might not exist at all if a disease affects only people in low-resource settings.
PATH and our partners develop and advance affordable drugs to prevent and treat diseases that disproportionately affect people in low-income countries, including enteric and diarrheal diseases, neglected tropical diseases, HIV, and malaria. With an unshakeable commitment to health equity and a unique partnership approach spanning the academic, private, and nonprofit sectors, we are proving that it is possible to reach the world’s most vulnerable people with the medicines they need.
From investigation to delivery
PATH works to shepherd drugs through the journey of innovation to achieve successful, widespread uptake and sustainable impact. We develop and test solutions, navigate regulatory pathways for approval, address barriers to acceptance and use, and support countries and communities as they introduce new drugs.
On one end of the spectrum is our work to treat soil-transmitted helminths. These intestinal parasitic worms thrive in areas with limited sanitation and hygiene. They affect over a billion people worldwide, putting women and children, in particular, at risk for harmful, long-term effects. While treatment exists, there is concern that some worms are developing resistance. PATH is leading an international public-private partnership to investigate new drugs, as well as working to make an improved treatment more widely available.To save lives, a drug needs to reach the people who need it. PATH took the antiseptic chlorhexidine, which is used as a disinfectant in mouthwash and other health care products, and helped adapt it into a new, affordable formulation that can be used to cleanse babies’ newly cut umbilical cords. The new formulation has the potential to save millions of lives by preventing life-threatening infections. Now we are leading a movement to get chlorhexidine to health workers and others who support women during childbirth.
Partnering across sectors worldwide
PATH collaborates with global and country leaders to tackle head-on the tremendous need for affordable and effective drugs to treat diseases of poverty. We see drug development as a unique opportunity to use the power of innovation as a bridge connecting the best of the private and nonprofit sectors through a shared dedication to protecting health and saving lives.
Photo: PATH/Eric Becker.
Preventing umbilical cord infection with chlorhexidine
Artemisinin drug development
Creating a surer supply of the gold-standard malaria treatment
Prescription for a healthier world