Rethinking the Ethical Roadmap for Clinical Testing of Microbicides: Report on an International Consultation

On October 23–24, 2003, the Global Campaign for Microbicides brought together 64 people from 12 countries to rethink the issues and ethical dilemmas facing the field of microbicide development. The consultation comprised a broad range of stakeholders, including advocates, ethicists, clinical investigators, community members, drug regulatory authorities, and past participants in microbicide clinical trials. The report is available as one large file and as multiple smaller files for easier downloading.

Publication date: March 2005

Available materials

    1. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides (entire document) 1.1 MB PDF
    2. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Cover 129.5 KB PDF
    3. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Chapter 1. Introduction: Rethinking the Ethical Roadmap 182.1 KB PDF
    4. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Chapter 2. Background: How Microbicides are Developed and Tested 390.5 KB PDF
    5. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Chapter 3. The Shifting Focus of Ethical Concern: From Thinking About Risks to Thinking About Benefits 172.6 KB PDF
    6. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Chapter 4. How Informed is Informed Consent? 135.5 KB PDF
    7. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Chapter 5. What to Do About Male Partners? 156.1 KB PDF
    8. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Chapter 6. The Question of Enrolling Adolescents 179.9 KB PDF
    9. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Chapter 7. Defining "Benefits" and "Standard of Care" 222.5 KB PDF
    10. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Chapter 8. Antiretroviral Treatment in Clinical Trials 199.8 KB PDF
    11. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Chapter 9. Testing Second-Generation Microbicides 154.3 KB PDF
    12. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Chapter 10. After the Trial: Continued Access and Post-Approval Studies 136.6 KB PDF
    13. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Chapter 11. Conclusions and New Questions 109.4 KB PDF
    14. Rethinking the Ethical Roadmap for Clinical Testing of Microbicides - Appendixes 238.4 KB PDF