Between August 2004 and February 2005, the HIV prevention world was rocked by the suspension and cancellation of PrEP effectiveness trials in Cambodia and Cameroon. Acknowledging that no single version of the events constitutes the “real story,” the case studies are built from extensive interviews with researchers, policymakers, other government officials, donors, nongovernmental organization staff, and advocates to reconstruct often incompatible accounts of what eventually led to government intervention that halted the research. The case studies capture the political context and backdrop against which the controversies arose, the underlying and unaddressed conflicts that led to the costly collapse of two trials, and the lessons they provide for current and future research.
Preventing Prevention Trial Failures: A Case Study and Lessons for Future Trials from the 2004 Tenofovir Trail in Cambodia
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