With the sudden outbreak of the deadly COVID-19 pandemic that hit the world at the end of 2019, and the problems arising ever since, there is an urgent need for reliable and efficient laboratory tests to diagnose SARS-CoV-2, the virus that causes COVID-19. The crucial role played by laboratories in helping people obtain an accurate diagnosis and effective care has never been more evident than during the current pandemic.

This document aims to provide complete and accessible information about COVID-19 and its diagnosis. Created especially for laboratory personnel and stakeholders involved in laboratory work, this “handbook” on COVID-19 Testing on COVID-19 testing includes guidance on various diagnostic techniques for COVID-19. Aside from providing basic information about COVID-19 testing techniques and biosafety measures, this report also covers information about the standard procedures needed to set up a COVID-19 laboratory and how to carry out validation and approval of test kits for COVID-19 using antigen rapid diagnostic tests (Ag-RDTs) and molecular diagnostics, like polymerase chain reaction (PCR).

It is hoped that this document will act as a handy and useful guide for laboratory personnel involved in COVID-19 diagnosis.