Development of Modified Alkaline Lysis—Magnetic Bead Extraction of DNA for Molecular Diagnosis of Soil-Transmitted Helminths From Stool

Soil-transmitted helminths (STH) are parasitic intestinal worms that are controlled with mass drug administration in at-risk populations. The work described in this poster aims to develop a rapid, field-deployable, non-instrumented, magnetic bead-based protocol to extract STH egg DNA in stool, using Ascaris suum as model species, for use as a companion tool to recombinase polymerase amplification (RPA)-based diagnostics for STH.

Publication date: November 2016

Development of Modified Alkaline Lysis—Magnetic Bead Extraction of DNA for Molecular Diagnosis of Soil-Transmitted Helminths From Stool

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