An expert consultation was held in April 2015 to review equipment solutions to the problem of vaccines being exposed to sub-zero temperatures while being transported in passive vaccine carriers. Experts compared different approaches and reviewed three novel technology solutions: a freeze-safe vaccine carrier, phase-change material coolant packs, and a phase-change material sleeve. In addition, participants helped develop a generic evaluation framework for assessing these and other innovative approaches, and outlined the steps necessary to get them to market.