This special issue of Directions in Global Health features PATH's work in women's health. Featured projects include Sure Start; the Maternal and Newborn Health Technology Initiative; the Prevention of Postpartum Hemorrhage Initiative; Global Campaign for Microbicides; SILCS diaphragm; the PATH Woman's Condom; microbicide applicators; AIDS, Population, and Health Integrated Assistance II Western Province; and Spring Bud Healthy Development.