Presentation and packaging
The way that vaccines are formulated, packaged, and labeled can dramatically impact the success of their use, particularly in low-resource settings. The number of doses per container affects vaccine wastage rates and cold chain space requirements. A decision to provide a vaccine in a freeze-dried format usually has a positive outcome in terms of enhanced stability but requires that the vaccine be provided in two containers (one for the freeze-dried vaccine and the other for the diluents) with an added reconstitution step prior to administration. Minimizing the volumes of vaccine containers and packaging can help to reduce negative environmental impacts, shipping and storage costs, and the potential for preparation errors at the point of use.
The handling, management, and use of vaccines are becoming increasingly complex as more new vaccines and related technologies become available. PATH is working to optimize the presentation and packaging for new vaccines through participation in the Vaccine Presentation and Packaging Advisory Group. PATH is also developing and advancing innovations in the formulation, presentation, and delivery of vaccines with which it is involved. Visit PATH’s website to learn more about its general work in vaccine presentation and packaging, and more specific work in primary container packaging.
Desirable Attributes of Vaccines for Deployment in Low-Resource Settings (2013)
An article that discusses the opportunities and challenges associated with developing vaccines with desirable attributes, including efficient packaging.
Vaccine Presentation and Packaging Advisory Group: A Forum for Reaching Consensus on Vaccine Product Attributes (2012)
An article that describes a novel approach to improving vaccine design and presentation in order to reach all children with lifesaving vaccines.
Featured PATH resources
Some Vaccine Costs Are Hidden Below the Surface (2013)
A banner that illustrates the costs associated with different types of vaccine presentations.
Vaccine Presentation Assessment Tool (2010)
A tool designed to model the impact of adding new vaccines, with alternative presentations and packaging, to an immunization schedule.
Page last updated: November 2013.