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Sustained Reductions in Invasive Pneumococcal Disease in the Era of Conjugate Vaccine

This article, published in The Journal of Infectious Diseases, discusses a study examining invasive pneumococcal disease (IPD) cases from 1998 to 2007 from eight sites across the United States to assess the impact of 7-valent pneumococcal conjugate vaccine (PCV-7) introduction. The study finds that seven years after the introduction of PCV-7, an estimated 211,000 fewer cases and 13,000 fewer deaths have occurred. The authors also conclude that although IPD rates caused by serotype 19A and non-PCV7 types have risen, these rates remain low relative to decreases in PCV7-type IPD.

Author: Pilishvili T, Lexau C, Farley MM, et al.

Published: 2010

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(Located at www.journals.uchicago.edu)

Citation: Pilishvili T, Lexau C, Farley MM, et al. Sustained Reductions in Invasive Pneumococcal Disease in the Era of Conjugate Vaccine. Journal of Infectious Diseases. 2010;201(1):32-41.

Resource types: Peer-reviewed journal

Diseases/vaccines: Pneumococcus

Topics: Disease burden and surveillance, Disease/vaccine specific information

Regions: North America and Europe