This article, published in the Journal of Experimental Medicine, discusses a small-scale field trial that was carried out in United States military recruits to test the effect of immunization with meningococcal C polysaccharide upon the acquisition of group C meningococci. Over the course of the study, the proportion of unvaccinated recruits who acquired group C meningococci in the three companies studied was 38, 42, and 69 percent. A significantly lower proportion of the individuals vaccinated with group C polysaccharide acquired group C meningococci: 4.6, 24, and 31 percent, respectively.

Author(s): Gotschlich EC, Goldschneider I, Artenstein MS

Published: 1969

Resource types: Peer-reviewed journal

Diseases: Meningococcus

Topics: Disease/vaccine specific information

Regions: North America and Europe