PATH | VRL
Menu

Immune Response to Revaccination With Meningococcal A and C Polysaccharides in Gambian Children Following Repeated Immunization During Early Childhood

This article, published in the journal Vaccine, discusses a study of 42 Gambian children revaccinated at age five with meningococcal A/C polysaccharide vaccine (MPS) after receiving two doses of MPS in infancy and either MPS, meningococcal A/C conjugate, or inactivated polio vaccine at two years of age. The study found that multiple doses of meningococcal polysaccharide in childhood may weaken the bactericidal assay response to both group A and group C polysaccharides; however, vaccination with meningococcal A/C conjugate after MPS in infancy gives immunological memory to meningococcal group C. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: MacLennan J, Obaro S, Deeks J, et al.

Published: 1999

» Visit web page (English)

(Located at www.ncbi.nlm.nih.gov)

Citation: MacLennan J, Obaro S, Deeks J, et al. Immune Response to Revaccination With Meningococcal A and C Polysaccharides in Gambian Children Following Repeated Immunization During Early Childhood. Vaccine. 1999;17(23-24):3086-3093.

Resource types: Peer-reviewed journal

Diseases/vaccines: Meningococcus

Topics: Disease/vaccine specific information

Regions: Africa