Efficacy of RTS,S/AS01E Vaccine Against Malaria in Children 5 to 17 Months of Age

This study, published in the New England Journal of Medicine, evaluated the efficacy of the RTS,S malaria vaccine given with a more immunogenic adjuvant system (AS01E) than one used in a previous study (AS02A). The study was conducted in children 5 to 17 months of age in Kilifi, Kenya, and Korogwe, Tanzania, and concluded that RTS,S/AS01E shows promise as a candidate malaria vaccine.

Author(s): Bejon P, Lusingu J, Olotu A, et al.

Published: 2008

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    Citation: Bejon P, Lusingu J, Olotu A, et al. Efficacy of RTS,S/AS01E Vaccine Against Malaria in Children 5 to 17 Months of Age. New England Journal of Medicine. 2008;359(24):2521-2532.

Resource types: Peer-reviewed journal

Diseases: Malaria

Topics: Disease/vaccine specific information

Regions: Africa