Safety and Immunogenicity of RTS,S/AS02D Malaria Vaccine in Infants

This study, published in the New England Journal of Medicine, assessed the feasibility of integrating the RTS,S/AS02D malaria vaccine into a standard expanded program on immunization (EPI) schedule for infants. The study, conducted in Tanzania, showed that the use of the RTS,S/AS02D vaccine in infants had a promising safety profile, did not interfere with the immunologic responses to coadministered EPI antigens, and reduced the incidence of malaria infection.

Author(s): Abdulla S, Oberholzer R, Juma O, et al.

Published: 2008

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    (Located at content.nejm.org)

    Citation: Abdulla S, Oberholzer R, Juma O, et al. Safety and Immunogenicity of RTS,S/AS02D Malaria Vaccine in Infants. New England Journal of Medicine. 2008;359(24):2533-2544.