In this article, published in the Journal of Clinical Microbiology, researchers identified a broad diversity of rotavirus strains among children in India, including several unusual strains and two novel strains. The study highlights the great diversity among rotaviruses isolated from Indian children, the opportunity for genetic reassortment between strains, and the emergence of a novel G12 strain in India. Due to the demonstrated effect of antigenic diversity on rotavirus vaccines, it is important to continue careful monitoring of these strains as rotavirus vaccine programs are implemented in India.

Author(s): Sharma S, Ray P, Gentsch JR, Glass RI, Kalra V, Bhan MK

Published: 2008

Resource types: Peer-reviewed journal

Diseases: Rotavirus

Topics: Disease burden and surveillance; Disease/vaccine specific information

Regions: Asia