Enteric Infections, Diarrhea, and Their Impact on Function and Development

Enteric infections, with or without overt diarrhea, have profound effects on intestinal absorption, nutrition, and childhood development as well as on global mortality. Oral rehydration therapy has reduced the number of deaths from dehydration caused by infection with an enteric pathogen, but it has not changed the morbidity caused by such infections. This Review, published in The Journal of Clinical Investigation, focuses on the interactions between enteric pathogens and human genetic determinants that alter intestinal function and inflammation and profoundly impair human health and development.

Author(s): Petri Jr. WA, Miller M, Binder HJ, et al.

Published: 2008

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    Citation: Petri Jr. WA, Miller M, Binder HJ, et al. Enteric Infections, Diarrhea, and Their Impact on Function and Development. The Journal of Clinical Investigations. 2008;118(4):1277-1290.