Indirect Effects Associated with Widespread Vaccination of Infants with Heptavalent Pneumococcal Conjugate Vaccine (PCV7; Prevnar)

Published in the journal Vaccine, this review summarises published reports of invasive pneumococcal disease incidence (1998–2005) among non-immunised individuals in countries with universal PCV7 immunisation. Findings suggest that non-immunised individuals benefit from indirect protection following widespread vaccination, enhancing cost–benefit evaluations of vaccination programs. Continued surveillance will be important, to follow future changes associated with non-vaccine type IPD, particularly among individuals with medical co-morbidities that may put them at higher risk of disease.

Author(s): Isaacman DJ, Fletcher MA, Fritzell B, Ciuryla V, Schranz J

Published: 2007

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    Citation: Isaacman DJ, Fletcher MA, Fritzell B, Ciuryla V, Schranz J. Indirect Effects Associated with Widespread Vaccination of Infants with Heptavalent Pneumococcal Conjugate Vaccine (PCV7; Prevnar). Vaccine. 2007;25(13):2420-2427.