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Development of Lactococcal GEM-Based Pneumococcal Vaccines

Published in the journal Vaccine, this article reports on the development of a novel protein-based nasal vaccine against Streptococcus pneumoniae, in which three pneumococcal proteins were displayed on the surface of a non-recombinant, killed Lactococcus lactis-derived delivery system, called Gram-positive Enhancer Matrix (GEM).

Author: Audouy S, van Selm S, van Roosmalen M, et al.

Published: 2007

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(Located at www.sciencedirect.com)

Citation: Audouy S, van Selm S, van Roosmalen M, et al. Development of Lactococcal GEM-based Pneumococcal Vaccines. Vaccine. 2007;25(13):2497-2506.

Resource types: Peer-reviewed journal

Diseases/vaccines: Pneumococcus

Topics: Disease/vaccine specific information

Regions: Global