Two-Dose Schedules for Human Papillomavirus Vaccine: Systematic Review and Meta-Analysis
This article, published in Vaccine, reports the results of a study comparing the effects of a two-dose versus a three-dose immunization schedule for human papillomavirus (HPV) vaccine. According to the evidence systematically reviewed in this study, a two-dose HPV vaccine schedule in adolescent girls produces noninferior antibody responses compared to the standard three-dose schedule. Currently, global adoption of the two-dose schedule is limited, particularly in countries with the highest burden of cervical cancer.
Author: D'Addario M, Redmond S, Scott P, et al.
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Citation: D'Addario M, Redmond S, Scott P, et al. Two-Dose Schedules for Human Papillomavirus Vaccine: Systematic Review and Meta-Analysis. Vaccine. 2017;35(22):2892-2901.
Resource types: Peer-reviewed journal
Diseases/vaccines: Human papillomavirus (HPV)