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Global, Regional, and National Disease Burden Estimates of Acute Lower Respiratory Infections Due to Respiratory Syncytial Virus in Young Children in 2015: A Systematic Review and Modelling Study

This article, published in The Lancet, reports the results of a study estimating the global burden of respiratory syncytial virus (RSV) in young children, incorporating substantial new data from developing countries. The authors estimated that in 2015 there were more than 33 million episodes of RSV-associated acute lower respiratory infection (ALRI) globally, resulting in 3.2 million hospital admissions and nearly 120,000 deaths in children younger than five years of age. They conclude that RSV is a common cause of ALRI and major cause of hospital admissions in young children and note than an effective maternal RSV vaccine or monoclonal antibody could have a substantial effect on disease burden in this age group.

Author: Shi T, McAllister DA, O’Brien KL, et al.

Published: 2017

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(Located at www.thelancet.com)

Citation: Shi T, McAllister DA, O’Brien KL, et al. Global, Regional, and National Disease Burden Estimates of Acute Lower Respiratory Infections Due to Respiratory Syncytial Virus in Young Children in 2015: A Systematic Review and Modelling Study. The Lancet. 2017;390(10098):946-958.

Resource types: Peer-reviewed journal

Diseases/vaccines: Respiratory syncytial virus (RSV)

Topics: Disease burden and surveillance, Disease/vaccine specific information

Regions: Global