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The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine Effectiveness Study Designs: Accelerating the Introduction of Typhoid Conjugate Vaccines and Reducing the Global Burden of Enteric Fever. Report From a Meeting Held on 26–27 October 2016, Oxford, UK

This article, published in Vaccine, summarizes the results of a meeting held in October 2016 to initiate planning of typhoid conjugate vaccine (TCV) effectiveness studies that will provide the data required by policymakers and stakeholders to support decisions on TCV use in countries with a high typhoid burden. Participants discussed the latest evidence and data gaps in typhoid epidemiology, World Health Organization and Gavi, the Vaccine Alliance methods and data requirements, data on TCV efficacy, cost-effectiveness analysis for TCVs from mathematical models, and TCV delivery and effectiveness study design. Specifically, participants were asked to comment on study designs at three sites for which population-based typhoid surveillance is already underway.

Author: Meiring JE, Gibani M, TyVAC Consortium Meeting Group

Published: 2017

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(Located at www.sciencedirect.com)

Citation: Meiring JE, Gibani M, TyVAC Consortium Meeting Group. The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine Effectiveness Study Designs: Accelerating the Introduction of Typhoid Conjugate Vaccines and Reducing the Global Burden of Enteric Fever. Report From a Meeting Held on 26-27 October 2016, Oxford, UK. Vaccine. 2017;Early Online Publication. 

 

Resource types: Peer-reviewed journal

Diseases/vaccines: Typhoid

Topics: Immunization financing, Disease burden and surveillance, Vaccine safety and performance, Disease/vaccine specific information

Regions: Global