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Typhoid Fever and Paratyphoid Fever: Systematic Review to Estimate Global Morbidity and Mortality for 2010

This article, published in the Journal of Global Health, summarizes the findings of a systematic literature review of population-based studies and country disease surveillance reports with typhoid and paratyphoid fever incidence data published between 1980 and 2009. The authors grouped the input data into regions and estimated regional and global age-specfic incidence and mortality rates for typhoid and paratyphoid fever, extrapolating incidence data across regions for those lacking data. The estimated total number of typhoid fever episodes in 2010 was 13.5 million (interquartile range 9.1–17.8 million), and the adjusted estimate accounting for the low sensitivity of blood cultures for isolation of the bacteria was 26.9 million (interquartile range 18.3–35.7 million) episodes. The authors conclude that typhoid fever remains a significant health burden, especially in low- and middle-income countries, but that additional research is needed in many regions.

Author: Buckle GC, Fischer Walker CL, Black RE

Published: 2012

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(Located at www.ncbi.nlm.nih.gov)

Citation: Buckle GC, Fischer Walker CL, Black RE. Typhoid Fever and Paratyphoid Fever: Systematic Review to Estimate Global Morbidity and Mortality for 2010. Journal of Global Health. 2012;2(1):010401.

Resource types: Peer-reviewed journal

Diseases/vaccines: Typhoid

Topics: Disease burden and surveillance, Disease/vaccine specific information

Regions: Global