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Disease Burden of Group B Streptococcus Among Infants in Sub-Saharan Africa: A Systematic Literature Review and Meta-Analysis

Group B streptococcus (GBS) is a leading neonatal sepsis pathogen, and investment in disease prevention, such as maternal vaccination, requires evidence of disease burden. This article, published in The Pediatric Infectious Disease Journal, reports the results of a study to estimate maternal colonization proportion, GBS disease incidence, and GBS serotype distribution in sub-Saharan Africa. The authors found that despite methodological factors leading to underestimation, GBS disease incidence was shown to be high. The article suggests that safe, effective, and affordable disease prevention is needed. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: Sinha A, Russell LB, Tomczyk S, et al.

Published: 2016

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(Located at journals.lww.com)

Citation: Sinha A, Russell LB, Tomczyk S, et al. Disease Burden of Group B Streptococcus Among Infants in Sub-Saharan Africa: A Systematic Literature Review and Meta-Analysis. Pediatric Infectious Disease Journal. 2016;35(9):933-942. 

Resource types: Peer-reviewed journal

Diseases/vaccines: Group B Streptococcus (GBS)

Topics: Disease burden and surveillance, Disease/vaccine specific information

Regions: Africa