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Defining Cases of Severe Pediatric Diarrhea for an Efficacy Trial of an Enterotoxigenic Escherichia coli (ETEC) Vaccine: Report on an International Workshop, Washington DC, March 2016

This article, published in Vaccine, reports the results of an expert workshop focused on the development of a severity scale specific to enterotoxigenic Escherichia coli (ETEC) that could be used to identify moderate-to-severe ETEC cases during a vaccine efficacy trial. The expert committee made several recommendations for an ETEC-specific severity scale and recommended that a validation study be considered in sub-Saharan Africa before being utilized in a Phase 3 ETEC vaccine study. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: Wierzba TF, Bourgis A, Steering Committee for Development of a Diarrhea Severity Scale

Published: 2017

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Citation: Wierzba TF, Bourgis A, Steering Committee for Development of a Diarrhea Severity Scale. Defining Cases of Severe Pediatric Diarrhea for an Efficacy Trial of an Enterotoxigenic Escherichia coli (ETEC) Vaccine: Report on an International Workshop, Washington DC, March 2016. Vaccine. 2017;35(4):503-507.

Resource types: Peer-reviewed journal

Diseases/vaccines: Shigellosis and enterotoxigenic Escherichia coli (ETEC)

Topics: Disease/vaccine specific information

Regions: Global