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The Infant Gut Microbiome Correlates Significantly With Rotavirus Vaccine Response in Rural Ghana

This article, published in the Journal of Infectious Diseases, reports the results of a study examining the differences in intestinal microbiome composition and rotavirus vaccine efficacy in developing-country settings. The authors found that the composition of the intestinal microbiome correlated significantly with rotavirus vaccine immunogenicity and may contribute to the diminished efficacy observed in developing countries.

Author: Harris VC, Armah G, Fuentes S, et al.

Published: 2016

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(Located at jid.oxfordjournals.org)

Citation: Harris VC, Armah G, Fuentes S, et al. The Infant Gut Microbiome Correlates Significantly With Rotavirus Vaccine Response in Rural Ghana. Journal of Infectious Diseases. 2016;Early Online Publication. 

Resource types: Peer-reviewed journal

Diseases/vaccines: Rotavirus

Topics: Vaccine safety and performance, Disease/vaccine specific information

Regions: Africa