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Preparation of a Respiratory Syncytial Virus Human Reference Serum for Use in the Quantitation of Neutralization Antibody

Currently, immune responses to experimental respiratory syncytial virus (RSV) vaccines are usually evaluated by two different assays, however both types are generally performed differently at different laboratories. This article, published in Biologicals, reports on work to prepare and characterize a human reference serum against the A2 strain of RSV. The reference serum can be used to standardize and normalize neutralization and/or other RSV-specific assay results from different laboratories. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: Yang DP, Zielinska E, Quiroz J, Madore D, Rappaport R

Published: 2007

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(Located at www.sciencedirect.com)

Citation: Yang DP, Zielinska E, Quiroz J, Madore D, Rappaport R. Preparation of a Respiratory Syncytial Virus Human Reference Serum for Use in the Quantitation of Neutralization Antibody. Biologicals. 2007;(35)3:183-187.

Resource types: Peer-reviewed journal

Diseases/vaccines: Respiratory syncytial virus (RSV)

Topics: Disease/vaccine specific information

Regions: Global