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Neutralizing Epitopes on the Respiratory Syncytial Virus Fusion Glycoprotein

The respiratory syncytial virus viral fusion glycoprotein (RSV F) is the major target of neutralizing antibodies, making it a target for vaccine development. This article, published in Current Opinion in Virology, summarizes recently determined structures of RSV F in prefusion and postfusion conformations and discusses how this influences vaccine development. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: McLellan JS

Published: 2015

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(Located at www.sciencedirect.com)

Citation: McLellan JS. Neutralizing Epitopes on the Respiratory Syncytial Virus Fusion Glycoprotein. Current Opinion in Virology. 2015;11:70-75.

Resource types: Peer-reviewed journal

Diseases/vaccines: Respiratory syncytial virus (RSV)

Topics: Disease/vaccine specific information

Regions: Global