PATH | VRL
Menu

The Biological Function of Antibodies Induced by the RTS,S/AS01 Malaria Vaccine Candidate is Determined by Their Fine Specificity

This article, published in Malaria Journal, discusses how recent vaccine studies have shown that the magnitude of an antibody response is often insufficient to explain efficacy, suggesting that characteristics regarding the quality of the antibody response, such as its fine specificity and functional activity, may play a major role in protection. It explores the relationship between fine specificity, opsonization-dependent phagocytic activity, and protection in RTS,S-induced antibodies. RTS,S is a malaria vaccine candidate.

Author: Chaudhury S, Ockenhouse CF, Regules JA, et al.

Published: 2016

» Visit web page (English)

(Located at malariajournal.biomedcentral.com)

Citation: Chaudhury S, Ockenhouse CF, Regules JA, et al. The Biological Function of Antibodies Induced by the RTS,S/AS01 Malaria Vaccine Candidate is Determined by Their Fine Specificity. Malaria Journal. 2016;15:301.

Resource types: Peer-reviewed journal

Diseases/vaccines: Malaria

Topics: Vaccine safety and performance, Disease/vaccine specific information

Regions: Global