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Optimization of a Membrane Feeding Assay for Plasmodium vivax Infection in Anopheles albimanus

Development of a malaria transmission blocking (TB) vaccine requires a better understanding of the mechanisms and main effectors responsible for TB responses. This article, published in PLOS Neglected Tropical Diseases, reports the results of a study to evaluate mosquito, vector, and parasite factors that may influence Anopheles mosquito infection in order to develop an efficient and reliable assay to assess TB immunity. The authors found that the membrane feeding assay method can contribute to better assess TB immune responses elicited by natural infection as well as further evaluation of protective efficacy of malaria TB vaccines.

Author: Vallejo AF, Rubiano K, Amado A, Krystosik AR, Herrera S, Arévalo-Herrera M

Published: 2016

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(Located at journals.plos.org)

Citation: Vallejo AF, Rubiano K, Amado A, Krystosik AR, Herrera S, Arévalo-Herrera M. Optimization of a Membrane Feeding Assay for Plasmodium vivax Infection in Anopheles albimanus. PLOS Neglected Tropical Diseases. 2016;10(6):e0004807.

Resource types: Peer-reviewed journal

Diseases/vaccines: Malaria

Topics: Disease/vaccine specific information

Regions: Latin America and the Caribbean