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Impact of Different Dosing Schedules on the Immunogenicity of the Human Rotavirus Vaccine in Infants in Pakistan: A Randomized Trial

This article, published in the Journal of Infectious Diseases, reports the results of a study examining the immunogenicity and efficacy of admininstering an additional dose of monovalent rotavirus vaccine in Pakistan. The authors found that a third dose of rotavirus vaccine did not significantly increase immunogenicity compared to two doses. Additional strategies should be evaluated for improving rotavirus vaccine immunogenicity in high-burden countries.

Author: Ali SA, Kazi AM, Cortese MM, et al.

Published: 2014

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(Located at jid.oxfordjournals.org)

Citation: Ali SA, Kazi AM, Cortese MM, et al. Impact of Different Dosing Schedules on the Immunogenicity of the Human Rotavirus Vaccine in Infants in Pakistan: A Randomized Trial. Journal of Infectious Diseases. 2014;210(11):1772-1779.

Resource types: Peer-reviewed journal

Diseases/vaccines: Rotavirus

Topics: Vaccine safety and performance, Disease/vaccine specific information

Regions: Asia