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Individual-Specific Changes in the Human Gut Microbiota After Challenge With Enterotoxigenic Escherichia coli and Subsequent Ciprofloxacin Treatment

This article, published in BMC Genomics, reports the results of a study that aimed to understand the impact of the human intestinal microbiota on the initiation and progression of enterotoxigenic Escherichia coli (ETEC) diarrhea. The authors found that symptomatic ETEC infections, but not asymptomatic infections, were associated with high fecal concentrations of E. coli. Infection and treatment with antibiotics caused variable changes in the intestinal microbiota that generally reverted to baseline levels after three months.

Author: Pop M, Paulson JN, Chakraborty S, et al.

Published: 2016

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(Located at bmcgenomics.biomedcentral.com)

Citation: Pop M, Paulson JN, Chakraborty S, et al. Individual-Specific Changes in the Human Gut Microbiota After Challenge With Enterotoxigenic Escherichia coli and Subsequent Ciprofloxacin Treatment. BMC Genomics. 2016;17:440.

Resource types: Peer-reviewed journal

Diseases/vaccines: Shigellosis and enterotoxigenic Escherichia coli (ETEC)

Topics: Disease/vaccine specific information

Regions: Global