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Effect of the Introduction of Pneumococcal Conjugate Vaccination on Invasive Pneumococcal Disease in The Gambia: A Population-Based Surveillance Study

Little information is available about the effect of pneumococcal conjugate vaccines (PCVs) in low-income countries. This article, published in The Lancet Infectious Diseases, presents the results of a study that measured the effects of PCVs on invasive pneumococcal disease in The Gambia where the 7-valent vaccine (PCV7) was introduced in August 2009, followed by the 13-valent vaccine (PCV13) in May 2011. The results showed that the use of PCV in The Gambia reduced severe pneumococcal pneumonia, sepsis, and meningitis in children aged 2 to 59 months by 55 percent, indicating the real-life impact of PCV in a developing country. The authors conclude that low- and middle-income countries that introduce PCV13 can expect similar substantial reductions in invasive pneumococcal disease.

Author: Mackenzie GA, Hill PC, Jeffries DJ, et al.

Published: 2016

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(Located at www.thelancet.com)

Citation: Mackenzie GA, Hill PC, Jeffries DJ, et al. Effect of the Introduction of Pneumococcal Conjugate Vaccination on Invasive Pneumococcal Disease in The Gambia: A Population-Based Surveillance Study. The Lancet Infectious Diseases. 2016;Early Online Publication.

Resource types: Peer-reviewed journal

Diseases/vaccines: Pneumococcus

Topics: Introduction and service delivery, Vaccine safety and performance, Disease/vaccine specific information

Regions: Africa