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Current Progress in Developing Subunit Vaccines Against Enterotoxigenic Escherichia coli-Associated Diarrhea

This article, published in Clinical and Vaccine Immunology, reports on the development status of subunit vaccines against enterotoxigenic Escherichia coli (ETEC). Currently, there are no available vaccines against ETEC-associated diarrhea. Whole-cell vaccine candidates have been under development but require further improvements because they provide inadequate protection and produce unwanted adverse effects. Results from recent studies suggest that polypeptide or subunit vaccines have the potential to effectively protect against ETEC diarrhea.

Author: Zhang W, Sack DA

Published: 2015

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(Located at cvi.asm.org)

Citation: Zhang W, Sack DA. Current Progress in Developing Subunit Vaccines Against Enterotoxigenic Escherichia coli-Associated Diarrhea. Clinical and Vaccine Immunology. 2015;22(9):983-991.

Resource types: Peer-reviewed journal

Diseases/vaccines: Shigellosis and enterotoxigenic Escherichia coli (ETEC)

Topics: Vaccine safety and performance, Disease/vaccine specific information

Regions: Global