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Transplacental Transport of IgG Antibodies to Preterm Infants: A Review of the Literature

This article, published in Early Human Development, summarizes a study that reviewed the transplacental transfer of immunoglobulin G against vaccine-preventable diseases (measles, rubella, varicella-zoster, mumps, Haemophilus influenzae type B, diphtheria, tetanus, pertussis, and polio) to (pre)term infants and to identify factors that influence the transplacental transfer of these antigens. The review included 18 studies on transplacental transport to preterm infants and found overall that preterm infants have lower antibody concentrations compared with term infants. Maternal and infants antibody concentrations showed a strong correlation in seven of the included studies. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: van den Berg JP, Westerbeek EAM, van der Klis FRM, Berbers GAM, van Elburg RM,

Published: 2011

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(Located at www.earlyhumandevelopment.com)

Citation: van den Berg JP, Westerbeek EAM, van der Klis FRM, Berbers GAM, van Elburg RM. Transplacental Transport of IgG Antibodies to Preterm Infants: A Review of the Literature. Early Human Development. 2011;87(2):67-72.

Resource types: Peer-reviewed journal

Diseases/vaccines: Polio

Topics: Disease/vaccine specific information

Regions: Global