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Correlates of Immunity to Respiratory Syncytial Virus (RSV) Associated-Hospitalization: Establishment of Minimum Protective Threshold Levels of Serum Neutralizing Antibodies

This article, published in Vaccine, reports on a study to determine if respiratory syncytial virus (RSV) specific, serum antibody titers correlate with protection against RSV-associated hospitalization at all ages. The authors identified a minimal protective threshold against RSV-associated hospitalizations, leading them to speculate that achieving this threshold antibody titer with a vaccine would significantly reduce RSV-associated hospitalization among all ages. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: Piedra PA, Jewell AM, Cron SG, Atmar RL, Glezen WP

Published: 2003

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(Located at www.sciencedirect.com)

Citation: Piedra PA, Jewell AM, Cron SG, Atmar RL, Glezen WP. Correlates of Immunity to Respiratory Syncytial Virus (RSV) Associated-Hospitalization: Establishment of Minimum Protective Threshold Levels of Serum Neutralizing Antibodies. Vaccine. 2003;21(24):3479-3482. 

Resource types: Peer-reviewed journal

Diseases/vaccines: Respiratory syncytial virus (RSV)

Topics: Disease/vaccine specific information

Regions: Global