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A 9-Valent HPV Vaccine Against Infection and Intraepithelial Neoplasia in Women

This article, published in the New England Journal of Medicine, reports on a study to determine the efficacy and immunogenicity of an investigational 9-valent human papillomavirus (HPV) vaccine in women 16 to 26 years of age. The authors found that the 9-valent vaccine prevented infection and disease related to HPV-31, 33, 45, 52, and 58 and generated an antibody response to HPV-6, 11, 16, and 18 that was noninferior to those generated by the existing quadrivalent HPV vaccine. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: Joura EA, Giuliano AR, Iversen O-E, et al.

Published: 2015

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(Located at www.nejm.org)

Citation: Joura EA, Giuliano AR, Iversen O-E, et al. A 9-Valent HPV Vaccine Against Infection and Intraepithelial Neoplasia in Women. New England Journal of Medicine. 2015;372(8):711-723.

Resource types: Peer-reviewed journal

Diseases/vaccines: Human papillomavirus (HPV)

Topics: Vaccine safety and performance, Disease/vaccine specific information

Regions: Global