Evaluating the Potential Risks and Benefits of Infant Rotavirus Vaccination in England

This article, published in Vaccine, reports on a risk-benefit analysis of rotavirus vaccination that compared potential vaccine-related risks with estimated vaccine benefits in the 2012 birth cohort in England. The authors estimate that rotavirus vaccine would prevent excess doctor visits, emergency room visits, and hospital admissions each year, which would result in estimated annual cost savings of more than £11 million. Additionally, they estimate 375 fewer rotavirus diarrhea hospital admissions for every additional intussusception admission. The authors conclude that the benefits of rotavirus vaccination would greatly exceed the potential risk in England. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author(s): Clark A, Jit M, Andrews N, Atchison C, Edmunds WJ, Sanderson C

Published: 2014

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    Citation: Clark A, Jit M, Andrews N, Atchison C, Edmunds WJ, Sanderson C. Evaluating the Potential Risks and Benefits of Infant Rotavirus Vaccination in England. Vaccine. 2014; Early Online Publication.