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Risk of Intussusception after Monovalent Rotavirus Vaccination

This article, published in the New England Journal of Medicine, reports on a study that examined the risk of intussusception after monovalent rotavirus vaccination in a population in the United States. In this prospective postlicensure study of more than 200,000 doses of monovalent rotavirus vaccine, the authors observed a significant increase in the rate of intussusception after vaccination (estimated to be 5.3 per 100,000 infants vaccinated), a risk that must be weighed against the benefits of preventing rotavirus-associated illness. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: Weintraub ES, Baggs J, Duffy J, et al.

Published: 2014

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(Located at www.nejm.org)

Citation: Weintraub ES, Baggs J, Duffy J, et al. Risk of Intussusception after Monovalent Rotavirus Vaccination. New England Journal of Medicine. 2014;370(6):513-519.

Resource types: Peer-reviewed journal

Diseases/vaccines: Rotavirus

Topics: Vaccine safety and performance, Disease/vaccine specific information

Regions: North America and Europe