Viral and Host Factors in Human Respiratory Syncytial Virus Pathogenesis

The authors of this article, published in the Journal of Virology, discuss the contributions of viral versus various host factors to respiratory syncytial virus (RSV) pathogenesis. The authors conclude that a better understanding of the viral and host determinants of RSV disease will be important for designing vaccines and therapeutic agents. In particular, defining the consequences of primary infection at a time of developmental and immunological immaturity may be a key to the riddle of RSV pathogenesis. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author(s): Collins PL, Graham BS

Published: 2008

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    (Located at jvi.asm.org)

    Citation: Collins PL, Graham BS. Viral and Host Factors in Human Respiratory Syncytial Virus Pathogenesis. Journal of Virology. 2008;82(5):2040–2055.