The authors of this article, published in the Journal of Virology, discuss the contributions of viral versus various host factors to respiratory syncytial virus (RSV) pathogenesis. The authors conclude that a better understanding of the viral and host determinants of RSV disease will be important for designing vaccines and therapeutic agents. In particular, defining the consequences of primary infection at a time of developmental and immunological immaturity may be a key to the riddle of RSV pathogenesis. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author(s): Collins PL, Graham BS

Published: 2008

Resource types: Peer-reviewed journal

Diseases: Respiratory syncytial virus (RSV)

Topics: Disease/vaccine specific information

Regions: Global