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Duration of Protection of Pentavalent Rotavirus Vaccination in Nicaragua

This article, published in Pediatrics, summarizes a case-control study conducted at four hospitals in Nicaragua to evaluate the duration of protection after rotavirus vaccination among eligible infants. The pentavalent rotavirus vaccine protected against severe rotavirus during the first year of life, when most severe and fatal disease in developing countries occurs. However, protection declined with age, and the authors encourage disease monitoring among older children as well as evaluation of a booster dose. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal articles.)

Author: Patel M, Pedreira C, De Oliveira LH, et al.

Published: 2012

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(Located at pediatrics.aappublications.org)

Citation: Patel M, Pedreira C, De Oliveira LH, et al. Duration of Protection of Pentavalent Rotavirus Vaccination in Nicaragua. Pediatrics. 2012; Online Publication.

Resource types: Peer-reviewed journal

Diseases/vaccines: Rotavirus

Topics: Disease/vaccine specific information

Regions: Latin America and the Caribbean